The Jackson Laboratory

Center for Biometric Analysis

What We Do

At the Center for Biometric Analysis (CBA), we empower JAX scientists with cutting-edge in vivo mouse phenotyping services. Our expertise spans a wide range of biological domains and disease states. Beyond data acquisition, we offer comprehensive support through experimental design consultation, staff training, and rigorous data quality control, statistical analysis, and interpretation.

Services and Technologies Offered

The CBA offers comprehensive in vivo mouse phenotyping services through four specialized cores:

  • Neurobehavioral Phenotyping (NBP core)
  • Physiology and Cardiac Phenotyping (PCP core)
  • Metabolic Phenotyping (MEP core)
  • Pre-clinical Imaging (PCI core)

Each core provides a range of services tailored to specific research needs. As our equipment and technologies evolve, the services we offer may also change to ensure we continue to meet the highest standards of scientific research.

Assays By Biological Domain (CORE Service)

NBP Circadian Activity Monitoring (Wheels)

PCP Intraocular Pressure Measurement, Non-Invasive

NBP Elevated Zero Maze

PCP Optical Coherence Tomography

NBP Delayed Spatial Alternation (Y-Maze)

PCP Piezoelectric Sleep Monitoring

NBP Fear Conditioning, Contextual and Cued

PCP Slit Lamp Ophthalmoscopy

NBP Frailty Screen

PCP Visual Acuity

NBP Gait Analysis (Treadscan)

PCP Visual Evoked Potential

NBP Grip Strength

MEP Body Composition Analysis-EchoMRI

NBP Grooming, Induced and Spontaneous

MEP Body Weight

NBP Home Cage Monitoring (Phenotypers)

MEP Indirect Calorimetry

NBP Home Cage Wheel Running (Wheels)

MEP Insulin Tolerance Test

NBP Hot Plate

MEP Glucose Tolerance Test-Intraperitoneal

NBP Light/Dark Box

MEP Glucose Tolerance Test-Oral

NBP Nest Building

MEP Glucose Tolerance Test with Insulin-Oral

NBP Novel Object Recognition

MEP Hyperglycemic Clamps (Glucose Clamps)

NBP Open Field

MEP Mixed Meal Tolerance Test

NBP Passive Avoidance

MEP Mixed Meal Tolerance Test with C-peptide

NBP Place Object Recognition

MEP Treadmill Activity

NBP Pre-pulse Inhibition/Startle Reflex

PCI MRI-Anatomical

NBP Rotarod

PCI MRI-Angiography

NBP Social Approach (3-Chamber)

PCI MRI-Diffusion Tensor Imaging

NBP Spontaneous Alternation-Visual Cues (Y-Maze)

PCI MRI-Diffusion Weighted Imaging, Isotropic

NBP Tail Withdrawal

PCI MRI-Neurite Orientation Dispersion and Density Imaging

NBP Von Frey

PCI MRI-Neuroanatomical

PCP Auditory Brainstem Response

PCI MRI-Neuroanatomical, Isotropic

PCP Blood Pressure, Non-Invasive

PCI MRI-Resting State Functional (rsfMRI)

PCP Direct & Indirect Ophthalmic Exam

PCI MRI-rsfMRI, Isotropic (imaging acquisition only)

PCP Distortion Product Otoacoustic Emission

PCI MRI Susceptibility Weighted Imaging

PCP DSI Telemetry Cardiovascular Blood Pressure

PCI MRI-T2star Mapping, Isotropic

PCP DSI Telemetry EEG/EMG-Deep Brain EEG

PCI uCT-in vivo Imaging

PCP DSI Telemetry EEG/EMG-Seizures

PCI uCT-ex vivo Imaging (Trabecular and Cortical Bone Quantification)

PCP DSI Telemetry EEG/EMG-Sleep

PCI 2D Digital X-ray Skeletal Imaging

PCP Electrocardiogram, Anesthetized

PCI Dual-Emission X-ray Absorptiometry

PCP Electroretinography

PCI Ultrasonography

PCP Fundus Imaging/Fluorescence Angiography

PCP Gross Morphology Photography

CBA_1 Anatomical NeuroMRI_800x450 - 1

CBA_2_Gait_800x450

CBA_3_Eye Composite_800x450

CBA_4_Novel Object_800x450

CBA_5_uCT Lean_Fat_800x450

CBA_6_YMaze_800x450

CBA_7_Echocardiogram_800x450

CBA_8 Running Wheels_800x450

CBA_9_Skull uCT_800x450

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